A methylbenzimidazole derivative regulates mammalian circadian rhythms by targeting Cryptochrome proteins [version 2; peer review: 2 approved]

Background: Impairment of the circadian clock has been associated with numerous diseases, including sleep disorders and metabolic disease. Although small molecules that modulate clock function may form the basis of drug discovery of clock-related diseases, only a few compounds that selectively targe...

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Bibliographic Details

Published in:	F1000Research
Main Authors:	Ayato Sato, Tsuyoshi Hirota, Yoshiko Nagai, Shinsuke Inuki, Moeri Yagi, Simon Miller
Format:	Article
Language:	English
Published:	F1000 Research Ltd 2022-10-01
Subjects:	Circadian clock Cryptochrome Small-molecule compound eng
Online Access:	https://f1000research.com/articles/11-1016/v2