Research progress of targeted therapy regulating Th17/Treg balance in bone immune diseases

Rheumatoid arthritis (RA) and postmenopausal osteoporosis (PMOP) are common bone-immune diseases. The imbalance between helper (Th17) and regulatory T cells (Tregs) produced during differentiation of CD4+ T cells plays a key regulatory role in bone remodelling disorders in RA and PMOP. However, the...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Xiaxia Wang, Bai Sun, Yujie Wang, Peng Gao, Jiayi Song, Weirong Chang, Zhipan Xiao, Yongbin Xi, Zhonghong Li, Fangyu An, Chunlu Yan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-01-01
Subjects:	rheumatoid arthritis postmenopausal osteoporosis targeted therapy Th17/Treg equilibrium bone immunity
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1333993/full