Human induced pluripotent stem cells derived neutrophils display strong anti-microbial potencies

Abstract Neutrophils are essential innate immune cells with unusual anti-microbial properties while dysfunctions of neutrophils lead to severe health problems such as lethal infections. Generation of neutrophils from human induced pluripotent stem cells (hiPSCs) is highly promising to produce off-th...

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Bibliographic Details

Published in:	Cell Regeneration
Main Authors:	Xing Hu, Baoqiang Kang, Mingquan Wang, Huaisong Lin, Zhiyong Liu, Zhishuai Zhang, Jiaming Gu, Yuchan Mai, Xinrui Guo, Wanli Ma, Han Yan, Shuoting Wang, Jingxi Huang, Junwei Wang, Jian Zhang, Tianyu Zhang, Bo Feng, Yanling Zhu, Guangjin Pan
Format:	Article
Language:	English
Published:	SpringerOpen 2025-03-01
Subjects:	hiPSCs Neutrophils Bacteria Cell therapy
Online Access:	https://doi.org/10.1186/s13619-025-00227-z