The study on the role of O-GlcNAcylation of SIRT3 in regulating mitochondrial oxidative stress during simulate myocardial ischemia-reperfusion

Abstract Myocardial ischemia-reperfusion injury (MIRI) is a significant complication following reperfusion therapy after myocardial infarction. Mitochondrial oxidative stress is a critical factor in MIRI, and Sirtuin 3 (SIRT3), as a major mitochondrial deacetylase, plays a key protective role, with...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Han Zhou, Yingjie Ji, Jingjie Li, Lin Sun
Format: Article
Language:English
Published: Nature Portfolio 2024-09-01
Subjects:
SI/R
SIRT3
O-GlcNAcylation
Online Access:https://doi.org/10.1038/s41598-024-72324-z

Internet

https://doi.org/10.1038/s41598-024-72324-z

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