CD49b, CD87, and CD95 Are Markers for Activated Cancer-Associated Fibroblasts Whereas CD39 Marks Quiescent Normal Fibroblasts in Murine Tumor Models

Fibroblasts are thought to be key players in the tumor microenvironment. Means to identify and isolate fibroblasts as well as an understanding of their cancer-specific features are essential to dissect their role in tumor biology. To date, the identification of cancer-associated fibroblasts is widel...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	David J. Agorku, Anne Langhammer, Ute Heider, Stefan Wild, Andreas Bosio, Olaf Hardt
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-08-01
Subjects:	cancer-associated fibroblasts normal fibroblasts subcutaneous 4T1 mouse tumor model subcutaneous CT26.WT mouse tumor model CD39 CD87
Online Access:	https://www.frontiersin.org/article/10.3389/fonc.2019.00716/full