Molecular mechanisms of novel selective glucocorticoid receptor agonist action in breast cancer cells

Introduction. Glucocorticoids (GC) are widely used in breast cancer (BC) therapy to reduce the side effects of cytostatic drugs and may exhibit antiproliferative effects on luminal BC cells. The biological action of GC is mediated by glucocorticoid receptor (GR) by two mechanisms: transrepression, w...

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Bibliographic Details

Published in:	Успехи молекулярной онкологии
Main Authors:	E. M. Zhidkova, V. P. Maksimova, D. D. Grigoreva, V. Z. Shirinian, M. G. Yakubovskaya, E. A. Lesovaya
Format:	Article
Language:	Russian
Published:	ABV-press 2024-10-01
Subjects:	breast cancer glucocorticoid glucocorticoid receptor metastasis selective glucocorticoid receptor agonist chemotherapy side effect
Online Access:	https://umo.abvpress.ru/jour/article/view/711