Development of a hypoxia-responsive macrophage prognostic model using single-cell and bulk RNA sequencing in pancreatic cancer.

<h4>Objective</h4>Pancreatic ductal adenocarcinoma (PDAC) is characterized by a low survival rate and limited responsiveness to current therapies. The role of hypoxia in the tumor microenvironment is critical, influencing tumor progression and therapy resistance. The aim of this study wa...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Heming Ge, Gerrit Wolters-Eisfeld, Thilo Hackert, Yuqiang Li, Cenap Güngör
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2025-01-01
Online Access:	https://doi.org/10.1371/journal.pone.0322618