Structure-function analyses of metal-binding sites of HypA reveal residues important for hydrogenase maturation in Helicobacter pylori.

The nickel-containing enzymes of Helicobacter pylori, urease and hydrogenase, are essential for efficient colonization in the human stomach. The insertion of nickel into urease and hydrogenase is mediated by the accessory protein HypA. HypA contains an N-terminal nickel-binding site and a dynamic st...

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書誌詳細

出版年:	PLoS ONE
主要な著者:	Faith C Blum, Heidi Q Hu, Stephanie L Servetas, Stéphane L Benoit, Robert J Maier, Michael J Maroney, D Scott Merrell
フォーマット:	論文
言語:	英語
出版事項:	Public Library of Science (PLoS) 2017-01-01
オンライン･アクセス:	http://europepmc.org/articles/PMC5557546?pdf=render