Metabolic changes in children with idiopathic central precocious puberty after gonadotrophin-releasing hormone agonist therapy: a meta-analysis

BackgroundWe aimed to assess the effects of gonadotrophin-releasing hormone agonist (GnRHa) therapy on metabolic changes by synthesizing results from clinical trials involving children with idiopathic central precocious puberty (ICPP).MethodsLiterature search, trial selection, data extraction and qu...

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Bibliographic Details

Published in:	Frontiers in Pediatrics
Main Authors:	Bo Zhou, Xia Qu, Jianhong Wang, Qi Xu, Lili Zhang, Xi Wang, Nan Peng, Jialu Gu, Xiaoqian Zhang, Qiong Wang, Wenquan Niu, Lin Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Subjects:	gonadotrophin-releasing hormone agonists children idiopathic central precocious puberty metabolic changes meta-analysis
Online Access:	https://www.frontiersin.org/articles/10.3389/fped.2025.1519746/full