Myostatin-1 Inhibits Cell Proliferation by Inhibiting the mTOR Signal Pathway and MRFs, and Activating the Ubiquitin-Proteasomal System in Skeletal Muscle Cells of Japanese Flounder <i>Paralichthys olivaceus</i>

Myostatin (MSTN) is a negative regulator of skeletal muscle growth and development. The mechanisms of fish MSTN involved in muscle growth are not fully understood. In the present study, knockdown and overexpression of <i>mstn-1</i> was performed in cultured Japanese flounder muscle cells...

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Bibliographic Details

Published in:	Cells
Main Authors:	Jiahuan Liu, Mingzhu Pan, Dong Huang, Yanlin Guo, Mengxi Yang, Wenbing Zhang, Kangsen Mai
Format:	Article
Language:	English
Published:	MDPI AG 2020-10-01
Subjects:	myostatin muscle cell mTOR Forkhead box O1 ubiquitin-proteasomal system
Online Access:	https://www.mdpi.com/2073-4409/9/11/2376