Preparation and characterization of a iRGD-modified recombinant spider silk particles for antitumor polypeptide drug delivery into cancer cells

Abstract Spider silk is highly attractive material because of its superior mechanical properties and excellent biocompatibility, enabling it to self-assemble into a wide range of morphological structures for drug delivery system. However, most spider silk particles developed as drug carriers are bas...

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Bibliographic Details

Published in:	BMC Biotechnology
Main Authors:	Ben Wang, Hongbo Li, Ying Chen, Zhi Chen, Pingping Li, Xi Zhang, Xiaoji Lin
Format:	Article
Language:	English
Published:	BMC 2025-08-01
Subjects:	Spider silk particle iRGD Antitumor polypeptide Drug delivery Controlled release
Online Access:	https://doi.org/10.1186/s12896-025-01023-y