Fresh Medium or L-Cystine as an Effective Nrf2 Inducer for Cytoprotection in Cell Culture

The Nrf2 gene encodes a transcription factor best known for regulating the expression of antioxidant and detoxification genes. A long list of small molecules has been reported to induce Nrf2 protein via Keap1 oxidation or alkylation. Many of these Nrf2 inducers exhibit off-target or toxic effects du...

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Bibliographic Details
Published in:Cells
Main Authors: Wujing Dai, Qin M. Chen
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/2/291