Whole-transcriptome analysis of BLV-infected cows reveals downregulation of immune response genes in high proviral loads cows

Bovine leukemia virus (BLV) is a retrovirus that infects cattle, causing bovine enzootic leukosis, a chronic disease characterized by the proliferation of infected B cells. BLV proviral load (PVL) is a key determinant of disease progression and transmission risk. Cattle can exhibit distinct phenotyp...

Full description

Bibliographic Details

Published in:	Frontiers in Veterinary Science
Main Authors:	M. I. Petersen, G. Suarez Archilla, M. M. Miretti, K. G. Trono, H. A. Carignano
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Subjects:	BLV proviral load differential gene expression RNA-seq biological pathways analysis
Online Access:	https://www.frontiersin.org/articles/10.3389/fvets.2025.1550646/full