Circulating Cell-Free Mitochondrial DNA and Inflammation in Older Adults with Pancreatic Cancer: Results from an Exploratory Study

Pancreatic cancer (PaCa) is among the most aggressive malignancies of the digestive system. Inflammation plays a critical role in tumor growth and dissemination, with soluble cytokines serving as messengers that facilitate interactions between immune and cancer cells. The release of cell-free mitoch...

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Bibliographic Details

Published in:	Applied Sciences
Main Authors:	Giulia Girolimetti, Flora Guerra, Leonardo Henry Umberto Eusebi, Claudio Ricci, Emanuele Marzetti, Anna Picca, Cecilia Bucci
Format:	Article
Language:	English
Published:	MDPI AG 2025-04-01
Subjects:	cytokine damage-associated molecular patterns droplet digital PCR extracellular mtDNA macrophage tumor microenvironment
Online Access:	https://www.mdpi.com/2076-3417/15/8/4410