Lactylation of Mitochondrial Adenosine Triphosphate Synthase Subunit Alpha Regulates Vascular Remodeling and Progression of Aortic Dissection

Aortic dissection (AD) is a cardiovascular disorder with a high mortality rate. Lysine Lactylation (Kla), a novel posttranslational modification, critically regulates inflammation, tumors, and cardiovascular diseases. However, its specific role in AD pathogenesis remains unexplored. Using modificati...

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Bibliographic Details

Published in:	Research
Main Authors:	Tao Yu, Xiaolu Li, Chao Wang, Yanyan Yang, Xiuxiu Fu, Tianxiang Li, Wentao Wang, Xiangyu Liu, Xiaoxin Jiang, Ding Wei, Jian-Xun Wang
Format:	Article
Language:	English
Published:	American Association for the Advancement of Science (AAAS) 2025-01-01
Online Access:	https://spj.science.org/doi/10.34133/research.0799