Exploring SVA Insertion Polymorphisms in Shaping Differential Gene Expressions in the Central Nervous System

Transposable elements (TEs) are repetitive elements which make up around 45% of the human genome. A class of TEs, known as SINE-VNTR-Alu (SVA), demonstrate the capacity to mobilise throughout the genome, resulting in SVA polymorphisms for their presence or absence within the population. Although stu...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Lauren S. Hughes, Alexander Fröhlich, Abigail L. Pfaff, Vivien J. Bubb, John P. Quinn, Sulev Kõks
Format:	Article
Language:	English
Published:	MDPI AG 2024-03-01
Subjects:	SINE-VNTR-<i>Alu</i> transposable element whole-genome sequencing RNA-seq gene expression regulation expression quantitative trait loci
Online Access:	https://www.mdpi.com/2218-273X/14/3/358