POT1-TPP1 telomere length regulation and disease
Telomeres are DNA repeats at the ends of linear chromosomes and are replicated by telomerase, a ribonucleoprotein reverse transcriptase. Telomere length regulation and chromosome end capping are essential for genome stability and are mediated primarily by the shelterin and CST complexes. POT1-TPP1,...
| Published in: | Computational and Structural Biotechnology Journal |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-01-01
|
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037020303299 |