A feedback loop between plakophilin 4 and YAP signaling regulates keratinocyte differentiation
Summary: The Hippo signaling pathway is an important regulator of organ growth and differentiation, and its deregulation contributes to the development of cancer. The activity of its downstream targets YAP/TAZ depends on adherens junctions. Plakophilin 4 (PKP4) is a cell-type specific adherens junct...
| Published in: | iScience |
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| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-09-01
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| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004224019874 |