Apolipoprotein D is a component of compact but not diffuse amyloid-beta plaques in Alzheimer's disease temporal cortex

Apolipoprotein D (apoD) is elevated in Alzheimer's disease (AD) cortex, localizing to cells, blood vessels, and neuropil deposits (plaques). The role of apoD in AD pathology and the extent of its co-distribution with diffuse (amorphous) and compact (dense fibrillar) amyloid-beta (Aβ) plaques ar...

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Bibliographic Details

Published in:	Neurobiology of Disease
Main Authors:	Purnima P. Desai, Milos D. Ikonomovic, Eric E. Abrahamson, Ronald L. Hamilton, Barbara A. Isanski, Caroline E. Hope, William E. Klunk, Steven T. DeKosky, M. Ilyas Kamboh
Format:	Article
Language:	English
Published:	Elsevier 2005-11-01
Subjects:	Alzheimer's disease Amyloidosis Apolipoprotein Astrocyte Microglia Neuritic plaque
Online Access:	http://www.sciencedirect.com/science/article/pii/S096999610500121X