Sex-specific proximal tubular cell differentiation pathways identified by single-nucleus RNA sequencing

Abstract Postnatal kidney growth is substantial and involves expansion in kidney tubules without growth of new nephrons, which are the functional units of the kidney. Proliferation and differentiation pathways underpinning nephron elongation are not well defined. To address this, we performed sequen...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Yueh-An Lu, Tanya Smith, Sumukh Deshpande, Chia-Te Liao, Bnar Talabani, Irina Grigorieva, Anna Mason, Robert Andrews, Timothy Bowen, Philip R. Taylor, Donald Fraser
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-10-01
Subjects:	Cell biology and structure Chronic kidney disease Epithelial Kidney tubule MRNA Proximal tubule
Online Access:	https://doi.org/10.1038/s41598-024-73102-7