Integrating proteomics and network pharmacology to explore the relevant mechanism of Huangkui capsule in the treatment of chronic glomerulonephritis

IntroductionChronic glomerulonephritis (CGN) is a common glomerular disease with multifactorial pathogenesis. Huangkui capsule (HKC), a traditional Chinese herbal formulation, demonstrates therapeutic potential in CGN; however, its molecular mechanisms remain insufficiently characterized. This study...

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Published in:	Frontiers in Pharmacology
Main Authors:	Chang Qing Wen, Jia Zou, Jia Xuan Li, Fu Jiang Wang, Hai Tao Ge
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Subjects:	Huangkui capsule proteomics network pharmacology chronic glomerulonephritis mechanism
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1560420/full