Distinct genetic responses to fluoxetine sertraline and citalopram in mouse cortical neurons

Summary: Antidepressants are widely prescribed for treating major depressive disorder (MDD); however, their precise therapeutic mechanisms remain incompletely understood. A notable conundrum is the substantial heterogeneity in clinical efficacy among drugs targeting the same molecular pathway, such...

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Bibliographic Details

Published in:	iScience
Main Authors:	Hajime Yamamoto, Kentaro Abe
Format:	Article
Language:	English
Published:	Elsevier 2025-11-01
Subjects:	Pharmacology Natural sciences Biological sciences Neuroscience Molecular neuroscience
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004225020619