JC Virus Agnogene Regulates Histone-Modifying Enzymes via PML-NBs: Transcriptomics in VLP-Expressing Cells

JC virus (JCV) replicates within the nuclei of glial cells in the human brain and causes progressive multifocal leukoencephalopathy. JCV possesses a small, circular, double-stranded DNA genome, divided into early and late protein-coding regions. The non-coding control region (NCCR) functions bidirec...

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Bibliographic Details

Published in:	Viruses
Main Authors:	Yukiko Shishido-Hara, Takeshi Yaoi
Format:	Article
Language:	English
Published:	MDPI AG 2025-10-01
Subjects:	JC virus (JCV) promyelocytic leukemia (PML) promyelocytic leukemia nuclear bodies (PML-NBs) agnogene capsid proteins histone modification
Online Access:	https://www.mdpi.com/1999-4915/17/10/1399