Recent advances in polygenic scores: translation, equitability, methods and FAIR tools

Abstract Polygenic scores (PGS) can be used for risk stratification by quantifying individuals’ genetic predisposition to disease, and many potentially clinically useful applications have been proposed. Here, we review the latest potential benefits of PGS in the clinic and challenges to implementati...

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書誌詳細

出版年:	Genome Medicine
主要な著者:	Ruidong Xiang, Martin Kelemen, Yu Xu, Laura W. Harris, Helen Parkinson, Michael Inouye, Samuel A. Lambert
フォーマット:	論文
言語:	英語
出版事項:	BMC 2024-02-01
主題:	Polygenic score (PGS) Clinical utility FAIR (Findable Accessible Interoperable And Reusable)
オンライン･アクセス:	https://doi.org/10.1186/s13073-024-01304-9