Long-term survival and undetectable circulating tumor DNA following comprehensive involved site radiotherapy for oligometastases

Abstract Distant metastases account for ~ 90% of cancer deaths and major responses with systemic therapy alone for metastatic cancers are so rare that the National Cancer Institute launched the Exceptional Responders Initiative. Comprehensive involved site radiotherapy (ISRT) is a promising treatmen...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Rachel Radigan, Caleb S. Kao, Michael Krainock, Minetta C. Liu, Vani Gupta, Lauren Alexander, Symeon Missios, John Hsu, Ashish Sangal, Michael T. Milano, Johnny Kao
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Online Access:https://doi.org/10.1038/s41598-025-88266-z