Identification and Characterization of HIRIP3 as a Histone H2A Chaperone

HIRIP3 is a mammalian protein homologous to the yeast H2A.Z deposition chaperone Chz1. However, the structural basis underlying Chz’s binding preference for H2A.Z over H2A, as well as the mechanism through which Chz1 modulates histone deposition or replacement, remains enigmatic. In this study, we a...

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Bibliographic Details
Published in:Cells
Main Authors: Maria Ignatyeva, Abdul Kareem Mohideen Patel, Abdulkhaleg Ibrahim, Raed S. Albiheyri, Ali T. Zari, Ahmed Bahieldin, Christian Bronner, Jamal S. M. Sabir, Ali Hamiche
Format: Article
Language:English
Published: MDPI AG 2024-02-01
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Online Access:https://www.mdpi.com/2073-4409/13/3/273