Tissue-specific transcriptomic changes associated with AmBisome® treatment of BALB/c mice with experimental visceral leishmaniasis [version 1; peer review: 2 approved]

Background: Liposomal amphotericin B (AmBisome®) as a treatment modality for visceral leishmaniasis (VL) has had significant impact on patient care in some but not all regions where VL is endemic.  As the mode of action of AmBisome® in vivo is poorly understood, we compared the tissue-specific trans...

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Bibliographic Details

Published in:	Wellcome Open Research
Main Authors:	Sarah Forrester, Karin Siefert, Helen Ashwin, Najmeeyah Brown, Andrea Zelmar, Sally James, Dimitris Lagos, Jon Timmis, Mitali Chatterjee, Jeremy C. Mottram, Simon L. Croft, Paul M. Kaye
Format:	Article
Language:	English
Published:	Wellcome 2019-12-01
Online Access:	https://wellcomeopenresearch.org/articles/4-198/v1