Clustering analysis of microRNA and mRNA expression data from TCGA using maximum edge-weighted matching algorithms

Abstract Background microRNA (miRNA) is a short RNA (~ 22 nt) that regulates gene expression at the posttranscriptional level. Aberration of miRNA expressions could affect their targeting mRNAs involved in cancer-related signaling pathways. We conduct clustering analysis of miRNA and mRNA using expr...

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Bibliographic Details

Published in:	BMC Medical Genomics
Main Authors:	Lizhong Ding, Zheyun Feng, Yongsheng Bai
Format:	Article
Language:	English
Published:	BMC 2019-08-01
Subjects:	Cancer miRNAs and mRNAs Gene regulation BRCA TCGA Bipartite graph
Online Access:	http://link.springer.com/article/10.1186/s12920-019-0562-z