Novel 5-HT5A receptor antagonists ameliorate scopolamine-induced working memory deficit in mice and reference memory impairment in aged rats

Despite the human 5-HT5A receptor being cloned in 1994, the biological function of this receptor has not been extensively characterized due to a lack of specific ligands. We recently reported that the selective 5-HT5A receptor antagonist ASP5736 ameliorated cognitive impairment in several animal mod...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Journal of Pharmacological Sciences
المؤلفون الرئيسيون:	Mayako Yamazaki, Mayuko Okabe, Noriyuki Yamamoto, Junko Yarimizu, Katsuya Harada
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Elsevier 2015-03-01
الموضوعات:	5-HT5A receptor Cognitive impairment Y-maze Water maze Occupancy
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S1347861315000328