The Molecular Mechanisms Underlying Mitochondria-Associated Endoplasmic Reticulum Membrane-Induced Insulin Resistance

Mitochondria and the endoplasmic reticulum (ER) are connected at multiple sites via what are known as mitochondria-associated ER membranes (MAMs). These associations are known to play an important role in maintaining cellular homeostasis. Impaired MAM signaling has wide-ranging effects in many disea...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Han Cheng, Xiaokun Gang, Guangyu He, Yujia Liu, Yingxuan Wang, Xue Zhao, Guixia Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-11-01
Subjects:	mitochondria-associated endoplasmic reticulum membrane mitochondria endoplasmic reticulum insulin resistance type 2 diabetes endoplasmic reticulum stress
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2020.592129/full