Loss of LasR function leads to decreased repression of Pseudomonas aeruginosa PhoB activity at physiological phosphate concentrations

ABSTRACT The Pseudomonas aeruginosa LasR transcription factor plays a role in quorum sensing (QS) across phylogenetically distinct lineages. However, isolates with loss-of-function mutations in lasR (LasR– strains) are commonly found in diverse settings, including infections where they are associate...

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Bibliographic Details

Published in:	Journal of Bacteriology
Main Authors:	Amy Conaway, Dallas L. Mould, Igor Todorovic, Deborah A. Hogan
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-06-01
Subjects:	PhoB LasR PhoR quorum sensing phosphate scavenging phenazines
Online Access:	https://journals.asm.org/doi/10.1128/jb.00189-24