Single-cell transcriptomic insights into ccRCC: a stemness gene signature for prognosis and treatment response prediction

Abstract Clear cell renal cell carcinoma (ccRCC), the most prevalent renal malignancy, exhibits remarkable intratumoral heterogeneity that challenges precise prognostication and treatment stratification. Leveraging single-cell RNA sequencing (scRNA-seq) and an advanced artificial intelligence (AI)-d...

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Bibliographic Details

Published in:	Discover Oncology
Main Authors:	Jianhui Chen, Xinyi Wu, Guo Han, Chao Xu
Format:	Article
Language:	English
Published:	Springer 2025-10-01
Subjects:	Clear cell renal cell carcinoma CcRCC Machine learning Stemness genes signature
Online Access:	https://doi.org/10.1007/s12672-025-03664-z