Hyaluronan - a functional and structural sweet spot in the tissue microenvironment

Transition from homeostatic to reactive matrix remodeling is a fundamental adaptive tissue response to injury, inflammatory disease, fibrosis and cancer. Alterations in architecture, physical properties and matrix composition result in changes in biomechanical and biochemical cellular signaling. The...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	James eMonslow, Priya eGovindaraju, Ellen ePure'
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-05-01
Subjects:	Homeostasis Pathogenesis Matrix remodeling hyaluronan
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00231/full