Single-cell RNA and T-cell receptor sequencing unveil mycosis fungoides heterogeneity and a possible gene signature

BackgroundMycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma (CTCL). Comprehensive analysis of MF cells in situ and ex vivo is complicated by the fact that is challenging to distinguish malignant from reactive T cells with certainty.MethodsTo overcome this limitation, we...

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書誌詳細

出版年:	Frontiers in Oncology
主要な著者:	Nalini Srinivas, Lukas Peiffer, Kai Horny, Kuan Cheok Lei, Terkild B. Buus, Linda Kubat, Meng Luo, Menghong Yin, Ivelina Spassova, Antje Sucker, Farnoush Farahpour, Jan Kehrmann, Selma Ugurel, Elisabeth Livingstone, Thilo Gambichler, Niels Ødum, Jürgen C. Becker
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2024-08-01
主題:	CTCL heterogeneity malignant T cells single-cell RNA sequencing TCR sequencing gene signature
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1408614/full