Effect of Tetrodotoxin Pellets in a Rat Model of Postherpetic Neuralgia

Postherpetic neuralgia (PHN) is nerve pain caused by a reactivation of the varicella zoster virus. Medications are used to reduce PHN but their use is limited by serious side effects. Tetrodotoxin (TTX) is a latent neurotoxin that can block neuropathic pain, but its therapeutic index is only 3–5 tim...

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Bibliographic Details

Published in:	Marine Drugs
Main Authors:	Bihong Hong, Jipeng Sun, Hongzhi Zheng, Qingqing Le, Changsen Wang, Kaikai Bai, Jianlin He, Huanghuang He, Yanming Dong
Format:	Article
Language:	English
Published:	MDPI AG 2018-06-01
Subjects:	postherpetic neuralgia tetrodotoxin TTX pellets pharmacokinetics varicella-zoster virus
Online Access:	http://www.mdpi.com/1660-3397/16/6/195