Time-course transcriptome analysis of a double challenge bleomycin-induced lung fibrosis rat model uncovers ECM homoeostasis-related translationally relevant genes

Background Idiopathic pulmonary fibrosis (IPF) is an irreversible disorder with a poor prognosis. The incomplete understanding of IPF pathogenesis and the lack of accurate animal models is limiting the development of effective treatments. Thus, the selection of clinically relevant animal models endo...

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Bibliographic Details
Published in:BMJ Open Respiratory Research
Main Authors: Gino Villetti, Maurizio Civelli, Martina Bonatti, Vanessa Pitozzi, Paola Caruso, Silvia Pontis, Maria Gloria Pittelli, Caterina Frati, Chiara Mangiaracina, Costanza Anna Maria Lagrasta, Federico Quaini, Simona Cantarella, Simone Ottonello, Barbara Montanini, Marcello Trevisani
Format: Article
Language:English
Published: BMJ Publishing Group 2023-07-01
Online Access:https://bmjopenrespres.bmj.com/content/10/1/e001476.full