Chimpanzee adenoviral vectors as vaccines – challenges to move the technology into the fast lane

Introduction: In recent years, replication-defective chimpanzee-derived adenoviruses have been extensively evaluated as genetic vaccines. These vectors share desirable properties with human adenoviruses like the broad tissue tropism and the ease of large-scale manufacturing. Additionally, chimpanzee...

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Bibliographic Details

Published in:	Expert Review of Vaccines
Main Authors:	Alessandra Vitelli, Antonella Folgori, Elisa Scarselli, Stefano Colloca, Stefania Capone, Alfredo Nicosia
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2017-12-01
Subjects:	vaccine viral vector chimpanzee adenovirus immunity t-cells mucosal immunity
Online Access:	http://dx.doi.org/10.1080/14760584.2017.1394842