Noncanonical role for the host Vps4 AAA+ ATPase ESCRT protein in the formation of Tomato bushy stunt virus replicase.

Assembling of the membrane-bound viral replicase complexes (VRCs) consisting of viral- and host-encoded proteins is a key step during the replication of positive-stranded RNA viruses in the infected cells. Previous genome-wide screens with Tomato bushy stunt tombusvirus (TBSV) in a yeast model host...

Full description

Bibliographic Details

Published in:	PLoS Pathogens
Main Authors:	Daniel Barajas, Isabel Fernández de Castro Martín, Judit Pogany, Cristina Risco, Peter D Nagy
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-04-01
Online Access:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004087&type=printable