Soluble CD147 regulates endostatin via its effects on the activities of MMP-9 and secreted proteasome 20S

During progression of rheumatoid arthritis (RA), angiogenesis provides oxygen and nutrients for the cells’ increased metabolic demands and number. To turn on angiogenesis, pro-angiogenic factors must outweigh anti-angiogenic factors. We have previously shown that CD147/extracellular matrix metallopr...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Maya M. Rahat, Hala Sabtan, Elina Simanovich, Amir Haddad, Tal Gazitt, Joy Feld, Gleb Slobodin, Adi Kibari, Muna Elias, Devy Zisman, Michal A. Rahat
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-01-01
Subjects:	endostatin CD147/EMMPRIN MMP-9 secreted proteasome 20S fibroblasts-monocytes interactions angiogenesis
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1319939/full