Familial isolated pituitary adenoma is independent of Ahr genotype in a novel mouse model of disease

Human familial isolated pituitary adenoma (FIPA) has been linked to germline heterozygous mutations in the gene encoding the aryl hydrocarbon receptor-interacting protein (AIP, also known as ARA9, XAP2, FKBP16, or FKBP37). To investigate the hypothesis that AIP is a pituitary adenoma tumor suppresso...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Anna L. Shen, Susan M. Moran, Edward N. Glover, Bernice C. Lin, Patrick R. Carney, Christopher A. Bradfield
Format:	Article
Language:	English
Published:	Elsevier 2024-04-01
Subjects:	Pituitary Aryl hydrocarbon receptor Aryl hydrocarbon receptor interacting protein Aryl hydrocarbon receptor nuclear translocator Familial isolated pituitary adenoma Loss-of-heterozygosity
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844024042622