Durability and effectiveness of dual vs. triple therapy and tablet simplification in ART: findings from the Italian MOSAICO study

IntroductionTreatment optimization in people with HIV (PWH) has increasingly focused on reducing drug burden and improving regimen simplicity. However, comparative real-world evidence on dual therapy (DT) vs. triple therapy (TT), and single-tablet regimens (STR) vs. multi-tablet regimens (MTR), rema...

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الحاوية / القاعدة:	Frontiers in Pharmacology
المؤلفون الرئيسيون:	Daniele Mengato, Giacomo Berti, Andrea Francavilla, Silvia Michielan, Linda Cappellazzo, Laura Agnoletto, Maria Chiara Silvani, Marco Chiumente, Dario Gregori, Maria Mazzitelli, Francesca Venturini, Anna Maria Cattelan, the SIFaCT MOSAICO Study Group, Salvatore Agosta, Marina Allegrini, Marina Assirelli, Maria Rita Badagliacca, Giuliana Battagin, Giorgia Bo, Jenny Bolcato, Cristina Bitello, Raffaella Binazzi, Arianna Cadeddu, Marila Camboni, Francesca Cammalleri, Anila Corja, Marta Cappellini, Claudia Ciraldo, Nicolò de Gennaro, Maria Dell'Aera, Silvia Enisci, Giuseppina Emanuela Fassari, Sara Ferrari, Gabriele Fabbri, Michela Falciani, Roberta Fraccaroli, Anna Gagliardi, Giovanna Gandini, Veronica Gonzi, Giuseppe Greco, Clara La Bruna, Stefano Loiacono, Kety Luzi, Eleonora Magistrelli, Marina Malena, Paola Marini, Andrea Misin, Valentina Mureddu, Arianna Orcesi, Simonetta Palazzini, Clara Palmieri, Giulia Piazza, Mariantonietta Piccoli, Fabio Pieraccini, Francesco Pomarico, Giovanna Rametta, Roberta Rampazzo, Lucia Rossi, Aurora Scazzina, Chiara Scolamacchia, Martina Tegon, Sara Tordi, Dario Ventura, Salvatore Vitale, Anastasia Zoffoli
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Frontiers Media S.A. 2025-08-01
الموضوعات:	people with HIV single tablet regimen dual therapy HIV treatment switch therapy optimization
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1633968/full