The tumor suppressor CREBBP and the oncogene MYCN cooperate to induce malignant brain tumors in mice

Abstract The tumor suppressor and chromatin modifier cAMP response element-binding protein binding protein (CREBBP) and v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (MYCN), a member of the MYC oncogene family, are critically involved in brain development. Both genes are...

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Bibliographic Details

Published in:	Oncogenesis
Main Authors:	Melanie Schoof, Gefion Dorothea Epplen, Carolin Walter, Annika Ballast, Dörthe Holdhof, Carolin Göbel, Sina Neyazi, Julian Varghese, Thomas Karl Albert, Kornelius Kerl, Ulrich Schüller
Format:	Article
Language:	English
Published:	Nature Publishing Group 2023-07-01
Online Access:	https://doi.org/10.1038/s41389-023-00481-3