‘Nelfinavir sensitizes a clinically relevant chemo-radioresistant cervical cancer in-vitro model by targeting the AKT-USP15/USP11-HPV16 E6/E7 axis

Resistance to standard therapies is a major challenge in managing cervical cancer, often leading to systemic relapse. This study aimed to develop an in-vitro model of chemo-radioresistant cervical cancer that mimics clinical conditions and also explore the therapeutic potential of the repurposed dru...

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Bibliographic Details

Published in:	Biochemistry and Biophysics Reports
Main Authors:	Reshma Reddy, Vagmi Gaiwak, Jayant Sastri Goda, Tanuja Teni
Format:	Article
Language:	English
Published:	Elsevier 2025-06-01
Subjects:	Cervical cancer Chemo-radioresistance HPV16 E6/E7 In-vitro model Ionizing radiation Nelfinavir
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405580825000743