Exploring synergistic and antagonistic interactions in phage-antibiotic combinations against ESKAPE pathogens

ABSTRACT In the era of antimicrobial resistance, phage-antibiotic combinations offer a promising therapeutic option, yet research on their synergy and antagonism is limited. This study aims to assess these interactions, focusing on protein synthesis inhibitors and cell envelope-active agents against...

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Bibliographic Details

Published in:	Microbiology Spectrum
Main Authors:	Ashlan J. Kunz Coyne, Mirna Eshaya, Callan Bleick, Samantha Vader, Biswajit Biswas, Melanie Wilson, Michael V. Deschenes, Jose Alexander, Susan M. Lehman, Michael J. Rybak
Format:	Article
Language:	English
Published:	American Society for Microbiology 2024-10-01
Subjects:	bacteriophage antibiotic antagonism Staphylococcus aureus Enterococcus faecium Pseudomonas aeruginosa
Online Access:	https://journals.asm.org/doi/10.1128/spectrum.00427-24