Automated live-cell single-molecule tracking in enteroid monolayers reveals transcription factor dynamics probing lineage-determining function

Summary: Lineage transcription factors (TFs) provide one regulatory level of differentiation crucial for the generation and maintenance of healthy tissues. To probe TF function by measuring their dynamics during adult intestinal homeostasis, we established HILO-illumination-based live-cell single-mo...

Full description

Bibliographic Details

Published in:	Cell Reports
Main Authors:	Nike Walther, Sathvik Anantakrishnan, Thomas G.W. Graham, Gina M. Dailey, Robert Tjian, Xavier Darzacq
Format:	Article
Language:	English
Published:	Elsevier 2024-11-01
Subjects:	CP: Developmental biology CP: Genomics
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124724012658