Understanding and Exploiting the Effect of Tuberculosis Antimicrobials on Host Mitochondrial Function and Bioenergetics

Almost 140 years after its discovery, tuberculosis remains the leading infectious cause of death globally. For half a century, patients with drug-sensitive and drug-resistant tuberculosis have undergone long, arduous, and complex treatment processes with several antimicrobials that primarily functio...

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Bibliographic Details

Published in:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Christina Cahill, James Joseph Phelan, Joseph Keane
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-09-01
Subjects:	antimicrobials tuberculosis mitochondrial function bioenergetics oxidative phosphorylation glycolysis
Online Access:	https://www.frontiersin.org/article/10.3389/fcimb.2020.00493/full