High-Resolution Imaging of Tumor Spheroids and Organoids Enabled by Expansion Microscopy

Three-dimensional cell cultures are able to better mimic the physiology and cellular environments found in tissues in vivo compared to cells grown in two dimensions. In order to study the structure and function of cells in 3-D cultures, light microscopy is frequently used. The preparation of 3-D cel...

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Bibliographic Details

Published in:	Frontiers in Molecular Biosciences
Main Authors:	Steven J. Edwards, Valentina Carannante, Kyra Kuhnigk, Henrik Ring, Tatsiana Tararuk, Finn Hallböök, Hans Blom, Björn Önfelt, Hjalmar Brismar
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-09-01
Subjects:	expansion microscopy spheroid organoid lightsheet imaging
Online Access:	https://www.frontiersin.org/article/10.3389/fmolb.2020.00208/full