Frequency-dependent modulation of evoked potentials during GPi-DBS in pediatric dystonia

Abstract Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is an established treatment for dystonia, yet the neurophysiological mechanisms underlying frequency-dependent effects remain poorly understood. In this study, we investigate how different GPi-DBS frequencies modulate evoked...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Rahil Soroushmojdehi, Jessica S. L. Vidmark, S. Alireza Seyyed Mousavi, Sumiko Abe, Terence D. Sanger
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-09-01
Subjects:	Deep brain stimulation (DBS) Evoked potentials (EP) Pediatric dystonia Globus pallidus internus (GPi) Stimulation frequency Electrophysiology
Online Access:	https://doi.org/10.1038/s41598-025-18436-6