The KLF16/MYC feedback loop is a therapeutic target in bladder cancer

Abstract Background Bladder cancer (BLCA) is a common malignancy characterized by dysregulated transcription and a lack of effective therapeutic targets. In this study, we aimed to identify and evaluate novel targets with clinical potential essential for tumor growth in BLCA. Methods CRISPR-Cas9 scr...

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書誌詳細

出版年:	Journal of Experimental & Clinical Cancer Research
主要な著者:	Lisi Zheng, Jingxuan Wang, Shan Han, Li Zhong, Zefu Liu, Bin Li, Ruhua Zhang, Liwen Zhou, Xianchong Zheng, Zhenhua Liu, Cuiling Zeng, Ruonan Li, Yezi Zou, Liqin Wang, Yuanzhong Wu, Tiebang Kang
フォーマット:	論文
言語:	英語
出版事項:	BMC 2024-11-01
主題:	KLF16 MYC Bladder cancer BET inhibitors Chemotherapy sensitivity
オンライン･アクセス:	https://doi.org/10.1186/s13046-024-03224-3