Biology of Pellino1: a potential therapeutic target for inflammation in diseases and cancers

Pellino1 (Peli1) is a highly conserved E3 Ub ligase that exerts its biological functions by mediating target protein ubiquitination. Extensive evidence has demonstrated the crucial role of Peli1 in regulating inflammation by modulating various receptor signaling pathways, including interleukin-1 rec...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Lili Yan, Yueran Cui, Juan Feng
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-12-01
Subjects:	Peli1 ubiquitination IL-1R/TLRs NF-κB inflammation cancer
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1292022/full